[HTML][HTML] BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis
PA Edwards, HR Kast, AM Anisfeld - Journal of lipid research, 2002 - ASBMB
During the last three years there have been a plethora of publications on the liver X-
activated receptors (LXRα, NR1H3, and LXRβ, NR1H2), the farnesoid X-activated receptor
(FXR, NR1H4), and the pregnane X receptor (PXR, NR1I2) and the role these nuclear
receptors play in controlling cholesterol, bile acid, lipoprotein and drug metabolism. The
current interest in these nuclear receptors is high, in part, because they appear to be
promising therapeutic targets for new drugs that have the potential to control lipid …
activated receptors (LXRα, NR1H3, and LXRβ, NR1H2), the farnesoid X-activated receptor
(FXR, NR1H4), and the pregnane X receptor (PXR, NR1I2) and the role these nuclear
receptors play in controlling cholesterol, bile acid, lipoprotein and drug metabolism. The
current interest in these nuclear receptors is high, in part, because they appear to be
promising therapeutic targets for new drugs that have the potential to control lipid …
