Validation of a high-resolution X-ray computed tomography system to measure murine adipose tissue depot mass in situ and longitudinally
AL Hildebrandt, DM Kelly-Sullivan, SC Black - Journal of pharmacological …, 2002 - Elsevier
Introduction: Obesity is a significant public health concern with considerable academic and
industrial research effort underway to discover novel drugs to treat this disease. The aim of
this study was to validate a recently developed high-resolution X-ray computed tomography
(micro CT) system capable of measuring murine adipose tissue depot mass in situ. Methods:
The micro CT was used to generate a series of cross-sectional X-ray images from which
individual adipose tissue depot mass was quantified. Four individual adipose tissue depots …
industrial research effort underway to discover novel drugs to treat this disease. The aim of
this study was to validate a recently developed high-resolution X-ray computed tomography
(micro CT) system capable of measuring murine adipose tissue depot mass in situ. Methods:
The micro CT was used to generate a series of cross-sectional X-ray images from which
individual adipose tissue depot mass was quantified. Four individual adipose tissue depots …