Sleeping sickness in Europeans: a review of 109 cases.

AJ Duggan, MP Hutchinson - Journal of Tropical medicine and …, 1966 - cabdirect.org
AJ Duggan, MP Hutchinson
Journal of Tropical medicine and Hygiene, 1966cabdirect.org
Of the 109 cases of sleeping sickness reviewed, 90 have been taken from the literature, the
details of 7 cases are from hospital records and 12 others are based on the authors' own
experience. The frequency of the various signs and symptoms of African trypanosomiasis in
the group as a whole is described. The strong male preponderance (98 patients) is largely
related to the relative occupational risks of the two sexes in Africa. Most of the infections,
from both East and West Africa, were diagnosed by examination of blood films. With regard …
Abstract
Of the 109 cases of sleeping sickness reviewed, 90 have been taken from the literature, the details of 7 cases are from hospital records and 12 others are based on the authors' own experience. The frequency of the various signs and symptoms of African trypanosomiasis in the group as a whole is described. The strong male preponderance (98 patients) is largely related to the relative occupational risks of the two sexes in Africa. Most of the infections, from both East and West Africa, were diagnosed by examination of blood films.
With regard to the presenting symptoms no clinical feature of early sleeping sickness in Europeans is constant, save probably pyrexia, and only the trypanosomal" chancre" and the rash can be described as pathognomonic. The need for early diagnosis is emphasized by the statement that the case mortality of untreated sleeping sickness is probably over 90%. The patients under review are not classified into the categories of Gambian and Rhodesian types since the onset in Europeans is invariably acute even in the so called gambiense areas.
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