Astrocyte activation correlates with cytokine production in central nervous system of Trypanosoma brucei brucei-infected mice.
CA Hunter, FW Jennings, PG Kennedy… - … investigation; a journal …, 1992 - europepmc.org
CA Hunter, FW Jennings, PG Kennedy, M Murray
Laboratory investigation; a journal of technical methods and pathology, 1992•europepmc.orgBackground During the late-stage disease associated with human African trypanosomiasis,
caused by infection with either Trypanosoma gambiense or T. rhodesiense, parasites invade
the central nervous system (CNS), eventually leading to development of CNS pathology.
This can be exacerbated by subcurative chemotherapy. The mechanisms through which the
inflammatory processes within the CNS are controlled remain unclear.
caused by infection with either Trypanosoma gambiense or T. rhodesiense, parasites invade
the central nervous system (CNS), eventually leading to development of CNS pathology.
This can be exacerbated by subcurative chemotherapy. The mechanisms through which the
inflammatory processes within the CNS are controlled remain unclear.
Background
During the late-stage disease associated with human African trypanosomiasis, caused by infection with either Trypanosoma gambiense or T. rhodesiense, parasites invade the central nervous system (CNS), eventually leading to development of CNS pathology. This can be exacerbated by subcurative chemotherapy. The mechanisms through which the inflammatory processes within the CNS are controlled remain unclear.
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