No evidence of auditory dysfunction in guinea pigs immunized with myelin P0 protein
MR Boulassel, JM Guerit, S Denison… - Hearing research, 2001 - Elsevier
Recent data have focused on the peripheral nerve myelin glycoprotein P0 as a putative
autoantigen involved in the autoimmune etiology of some cases of Meniere's disease,
idiopathic sensorineural hearing loss and sudden deafness. To determine whether
antibodies to myelin P0 can alter cochlear function, 13 healthy guinea pigs were immunized
with purified porcine myelin P0 while 10 controls were injected with saline water. The
animals were then evaluated for evidence of evolving inner ear disease using …
autoantigen involved in the autoimmune etiology of some cases of Meniere's disease,
idiopathic sensorineural hearing loss and sudden deafness. To determine whether
antibodies to myelin P0 can alter cochlear function, 13 healthy guinea pigs were immunized
with purified porcine myelin P0 while 10 controls were injected with saline water. The
animals were then evaluated for evidence of evolving inner ear disease using …
