[HTML][HTML] Effect of LpA-I Composition and Structure on Cholesterol Transfer between Lipoproteins (∗)

QH Meng, DL Sparks, YL Marcel - Journal of Biological Chemistry, 1995 - ASBMB
The effect of high density lipoprotein composition on the rates of unesterified cholesterol
exchange between low density lipoproteins (LDL) and well-defined homogeneous discoidal
lipoproteins (LpA-I) reconstituted with phosphatidylcholine, cholesterol, and apolipoprotein
AI (apoA-I) has been investigated. LpA-I containing cholesterol and 2, 3, and 4 apoA-I
molecules per particle differed in their ability to accept or donate cholesterol. A significant
cholesterol exchange occurs between LDL and Lp2A-I (7.8 and 9.6 nm), while there is little …