Pancreas-specific venular labeling by monastral blue B in the BB rat: modulation by prostaglandins and their inhibitors
Y Kitagawa, J Desemone, JP Mordes - Immunopharmacology, 1993 - Elsevier
Leaky blood vessels in the microcirculation can be detected in vivo by injecting an animal
with colloidal pigments like Monastral blue B (MbB). We have previously used this labeling
method in the BB rat, an animal model of spontaneous autoimmune diabetes, and detected
increased vascular permeability restricted to the venules of the pancreas. The earlier data
suggested that pancreata of animals susceptible to labeling contain trapped intravascular
monocytes that are activated to release vasoactive mediators after phagocytosis of MbB. To …
with colloidal pigments like Monastral blue B (MbB). We have previously used this labeling
method in the BB rat, an animal model of spontaneous autoimmune diabetes, and detected
increased vascular permeability restricted to the venules of the pancreas. The earlier data
suggested that pancreata of animals susceptible to labeling contain trapped intravascular
monocytes that are activated to release vasoactive mediators after phagocytosis of MbB. To …
