Unrelated umbilical cord blood transplantation for an infant with β-thalassemia major

JG Hall, PL Martin, S Wood… - Journal of Pediatric …, 2004 - journals.lww.com
Background: β-thalassemia major, one of the most prevalent hemoglobinopathies
throughout the world, can be cured by allogeneic stem cell transplantation therapy. Many
patients, however, lack a suitably matched related donor. Unrelated umbilical cord blood
can be used as an alternative stem cell source for some of these patients. This report
describes the successful transplantation of a 2-month-old infant with β-thalassemia major
using partially HLA-matched unrelated umbilical cord blood. Methods: After cytoreduction …