Cetirizine reduces inflammatory cell recruitment and ICAM-1 (or CD54) expression on conjunctival epithelium in both early-and late-phase reactions after allergen …
G Ciprandi, S Buscaglia, G Pesce… - Journal of allergy and …, 1995 - Elsevier
Background: Allergen-specific conjunctival challenge (ASCC) is a safe and reproducible
experimental model of allergic conjunctivitis and a useful tool in the evaluation of
effectiveness and possible mechanisms of action of drugs commonly used in the treatment
of allergic diseases. Objective: The protective effect of cetirizine on inflammatory changes
after ASCC was assessed in 12 patients with rhinoconjunctivitis caused by Parietaria
judaica in a double-blind study. Methods: After a screening ASCC was performed, patients …
experimental model of allergic conjunctivitis and a useful tool in the evaluation of
effectiveness and possible mechanisms of action of drugs commonly used in the treatment
of allergic diseases. Objective: The protective effect of cetirizine on inflammatory changes
after ASCC was assessed in 12 patients with rhinoconjunctivitis caused by Parietaria
judaica in a double-blind study. Methods: After a screening ASCC was performed, patients …
