Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma
PJ Bryce, R Geha, HC Oettgen - Journal of allergy and clinical immunology, 2003 - Elsevier
Background: Histamine elicits many features of immediate hypersensitivity reactions. Recent
evidence indicates that H1 receptors modulate immune responses to antigens.
Desloratadine (DL), a new, long-acting, H1 receptor antagonist, has both a potent
antihistaminic function and anti-inflammatory properties. Objective: We sought to evaluate
the effect of DL on allergic-airway responses in mice after inhalation of the naturally
occurring aeroallergen Aspergillus fumigatus (Af) and to examine the effects of DL on …
evidence indicates that H1 receptors modulate immune responses to antigens.
Desloratadine (DL), a new, long-acting, H1 receptor antagonist, has both a potent
antihistaminic function and anti-inflammatory properties. Objective: We sought to evaluate
the effect of DL on allergic-airway responses in mice after inhalation of the naturally
occurring aeroallergen Aspergillus fumigatus (Af) and to examine the effects of DL on …
