Altered glomerular permselectivity and progressive sclerosis following extreme ablation of renal mass

JL Olson, TH Hostetter, HG Rennke, BM Brenner… - Kidney international, 1982 - Elsevier
JL Olson, TH Hostetter, HG Rennke, BM Brenner, MA Venkatachalam
Kidney international, 1982Elsevier
Methods Experiments were performed on adult male Munich-Wistar rats weighing 200 to
250 g. Group 1. Fifteen rats served as a control group and underwent laparotomy and sham
renal ablation by manipulation of both renal pedicles but without destruction of renal tissue.
These rats were allowed free access to water and a standard rat diet (Lab Blox, Allied Mills
Inc., Chicago, Illinois) both before and after surgery. They were studied 1 week after the
sham procedure.
Methods Experiments were performed on adult male Munich-Wistar rats weighing 200 to 250 g.
Group 1. Fifteen rats served as a control group and underwent laparotomy and sham renal ablation by manipulation of both renal pedicles but without destruction of renal tissue. These rats were allowed free access to water and a standard rat diet (Lab Blox, Allied Mills Inc., Chicago, Illinois) both before and after surgery. They were studied 1 week after the sham procedure.
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