[HTML][HTML] Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells

U Hasler, D Mordasini, M Bens, M Bianchi… - Journal of Biological …, 2002 - ASBMB
Fine regulation of water reabsorption by the antidiuretic hormone [8-arginine] vasopressin
(AVP) occurs in principal cells of the collecting duct and is largely dependent on regulation
of the aquaporin-2 (AQP2) water channel. AVP-inducible long term AQP2 expression was
investigated in immortalized mouse cortical collecting duct principal cells. Combined RNase
protection assay, Western blot, and immunofluorescence analyses revealed that
physiological concentrations of AVP added to the basal side, but not to the apical side, of …