[PDF][PDF] Humanized mice for modeling human infectious disease: challenges, progress, and outlook

N Legrand, A Ploss, R Balling, PD Becker, C Borsotti… - Cell host & …, 2009 - cell.com
N Legrand, A Ploss, R Balling, PD Becker, C Borsotti, N Brezillon, J Debarry, Y de Jong…
Cell host & microbe, 2009cell.com
Over 800 million people worldwide are infected with hepatitis viruses, human
immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually.
Here we discuss the potential and challenges of humanized mouse models for developing
effective and affordable therapies and vaccines, which are desperately needed to combat
these diseases.
Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.
cell.com