[HTML][HTML] Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
Y Liang, D Fotiadis, S Filipek, DA Saperstein… - Journal of Biological …, 2003 - ASBMB
G protein-coupled receptors (GPCRs), which constitute the largest and structurally best
conserved family of signaling molecules, are involved in virtually all physiological
processes. Crystal structures are available only for the detergent-solubilized light receptor
rhodopsin. In addition, this receptor is the only GPCR for which the presumed higher order
oligomeric state in native membranes has been demonstrated (Fotiadis, D., Liang, Y.,
Filipek, S., Saperstein, DA, Engel, A., and Palczewski, K.(2003) Nature 421, 127–128). Here …
conserved family of signaling molecules, are involved in virtually all physiological
processes. Crystal structures are available only for the detergent-solubilized light receptor
rhodopsin. In addition, this receptor is the only GPCR for which the presumed higher order
oligomeric state in native membranes has been demonstrated (Fotiadis, D., Liang, Y.,
Filipek, S., Saperstein, DA, Engel, A., and Palczewski, K.(2003) Nature 421, 127–128). Here …