Intensity-modulated radiation therapy for head and neck cancer: systematic review and meta-analysis
GN Marta, V Silva, H de Andrade Carvalho… - Radiotherapy and …, 2014 - Elsevier
Background and purpose Intensity-modulated radiation therapy (IMRT) provides the
possibility of dose-escalation with better normal tissue sparing. This study was performed to
assess whether IMRT can improve clinical outcomes when compared with two-dimensional
(2D-RT) or three-dimensional conformal radiation therapy (3D-CRT) in patients with head
and neck cancer. Methods and materials Only prospective phase III randomized trials
comparing IMRT with 2D-RT or 3D-CRT were eligible. Combined surgery and/or …
possibility of dose-escalation with better normal tissue sparing. This study was performed to
assess whether IMRT can improve clinical outcomes when compared with two-dimensional
(2D-RT) or three-dimensional conformal radiation therapy (3D-CRT) in patients with head
and neck cancer. Methods and materials Only prospective phase III randomized trials
comparing IMRT with 2D-RT or 3D-CRT were eligible. Combined surgery and/or …
