1H NMR relaxation times of skeletal muscle metabolites at 3 T
Magnetic Resonance Materials in Physics, Biology and Medicine, 2004•Springer
This study reports proton relaxation times of water and metabolites in soleus and tibialis
anterior muscles of young healthy volunteers at 3 T. The results are in agreement with data
reported for 1.5 and 4 T, showing a steady increase of spin-lattice relaxation times of water,
creatine and lipids with B 0 and no effect of B 0 on spin–spin relaxation. Comparison
between muscles revealed a longer spin–spin relaxation time of water in soleus than in
tibialis anterior muscle (31±1 ms vs. 28±1 ms, p< 0.05). These data can be applied to …
anterior muscles of young healthy volunteers at 3 T. The results are in agreement with data
reported for 1.5 and 4 T, showing a steady increase of spin-lattice relaxation times of water,
creatine and lipids with B 0 and no effect of B 0 on spin–spin relaxation. Comparison
between muscles revealed a longer spin–spin relaxation time of water in soleus than in
tibialis anterior muscle (31±1 ms vs. 28±1 ms, p< 0.05). These data can be applied to …
Abstract
This study reports proton relaxation times of water and metabolites in soleus and tibialis anterior muscles of young healthy volunteers at 3 T. The results are in agreement with data reported for 1.5 and 4 T, showing a steady increase of spin-lattice relaxation times of water, creatine and lipids with B 0 and no effect of B 0 on spin–spin relaxation. Comparison between muscles revealed a longer spin–spin relaxation time of water in soleus than in tibialis anterior muscle (31±1 ms vs. 28±1 ms, p<0.05). These data can be applied to relaxation correction for the absolute quantification of skeletal muscle metabolite concentrations and further sequence optimization.
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