[HTML][HTML] Standardization of pre-analytical variables in plasma microparticle determination: results of the International Society on Thrombosis and Haemostasis SSC …
R Lacroix, C Judicone, M Mooberry… - Journal of Thrombosis …, 2013 - Elsevier
Microparticles (MPs) are sub-micron sized vesicles released by activated or apoptotic cells.
They are generally defined as 0.1–1 μm membrane particles that expose the anionic
phospholipid phosphatidylserine (PS) and membrane antigens representative of their
cellular origin 1. It is now well recognized that MPs behave as vectors of bioactive
molecules, playing a role in blood coagulation, inflammation, cell activation and cancer
metastasis. In clinical practice, circulating MPs originating from blood and vascular cells are …
They are generally defined as 0.1–1 μm membrane particles that expose the anionic
phospholipid phosphatidylserine (PS) and membrane antigens representative of their
cellular origin 1. It is now well recognized that MPs behave as vectors of bioactive
molecules, playing a role in blood coagulation, inflammation, cell activation and cancer
metastasis. In clinical practice, circulating MPs originating from blood and vascular cells are …