The role of Schwann cell differentiation in perineural invasion of adenoid cystic and mucoepidermoid carcinoma of the salivary glands

XL Luo, MY Sun, CT Lu, ZH Zhou - … journal of oral and maxillofacial surgery, 2006 - Elsevier
Twenty cases of adenoid cystic carcinoma (ACC) and 18 cases of mucoepidermoid
carcinoma (MEC), were examined for expression of the Schwann cell markers S100 protein
and glial fibrillary acidic protein (GFAP) by immunohistochemical staining. The relationship
between expression of S100 and GFAP and the occurrence of perineural invasion was
assessed. Ultrastructural localization of S100 and GFAP was examined by immunoelectron
microscopy, and the co-expression of S100 and muscle actin by double fluorescence …