[HTML][HTML] Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients

M Fritsch, C Koliaki, R Livingstone, E Phielix… - The American journal of …, 2015 - Elsevier
Background: Impaired energy metabolism is a possible mechanism that contributes to
insulin resistance and ectopic fat storage. Objective: We examined whether meal ingestion
differently affects hepatic phosphorus metabolites in insulin-sensitive and insulin-resistant
humans. Design: Young, lean, insulin-sensitive humans (CONs)[mean±SD body mass index
(BMI; in kg/m 2): 23.2±1.5]; insulin-resistant, glucose-tolerant, obese humans (OBEs)(BMI:
34.3±1.7); and type 2 diabetes patients (T2Ds)(BMI: 32.0±2.4) were studied (n= 10/group) …