Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

A Polykratis, N Hermance, M Zelic… - The Journal of …, 2014 - journals.aai.org
A Polykratis, N Hermance, M Zelic, J Roderick, C Kim, TM Van, TH Lee, FKM Chan
The Journal of Immunology, 2014journals.aai.org
THL and MAK designed and generated the targeting construct and AP performed the gene
targeting in embryonic stem cells and generated the RIPK1 knock-in mice. FKMC provided
B13R-deficient virus and advice on design and interpretation of viral experiments. NH, MZ,
JR, AP, CK, and T.-MV performed the experiments. MAK and MP coordinated the project and
wrote the manuscript.
THL and MAK designed and generated the targeting construct and AP performed the gene targeting in embryonic stem cells and generated the RIPK1 knock-in mice. FKMC provided B13R-deficient virus and advice on design and interpretation of viral experiments. NH, MZ, JR, AP, CK, and T.-MV performed the experiments. MAK and MP coordinated the project and wrote the manuscript.
journals.aai.org