Hyper-IgE syndromes: recent advances in pathogenesis, diagnostics and clinical care
S Farmand, M Sundin - Current opinion in hematology, 2015 - journals.lww.com
S Farmand, M Sundin
Current opinion in hematology, 2015•journals.lww.comThe recent advances expand our understanding of HIES, and improve the diagnostics and
clinical care. Yet, more research is required to fully elucidate the specific infection
susceptibilities and lung complications, particularly in STAT3-deficient HIES. Future studies
also need to focus on clinical care and treatment of nonimmunologic features of HIES, as
well as on exploring curative treatments.
clinical care. Yet, more research is required to fully elucidate the specific infection
susceptibilities and lung complications, particularly in STAT3-deficient HIES. Future studies
also need to focus on clinical care and treatment of nonimmunologic features of HIES, as
well as on exploring curative treatments.
Summary
The recent advances expand our understanding of HIES, and improve the diagnostics and clinical care. Yet, more research is required to fully elucidate the specific infection susceptibilities and lung complications, particularly in STAT3-deficient HIES. Future studies also need to focus on clinical care and treatment of nonimmunologic features of HIES, as well as on exploring curative treatments.
Lippincott Williams & Wilkins