Toxic epidermal necrolysis in the absence of circulating T cells: A possible role for resident memory T cells
H Iriki, T Adachi, M Mori, K Tanese, T Funakoshi… - Journal of the American …, 2014 - jaad.org
A 60-year-old Japanese man with natural killer cell leukemia underwent SMILE
chemotherapy (dexamethasone, methotrexate, ifosfamide, L-asparaginase, etoposide). On
day 19 after initiation of chemotherapy, erythema appeared on the whole body associated
with a fever of 398C. Targetoid lesions and erosions developed on the trunk and extremities.
Erosions extended to the oral and genital mucosa, and covered more than 60% of the body
surface by day 25 (Fig 1, A). Blood work on day 18 showed profound leukocytopenia (\1.0 3 …
chemotherapy (dexamethasone, methotrexate, ifosfamide, L-asparaginase, etoposide). On
day 19 after initiation of chemotherapy, erythema appeared on the whole body associated
with a fever of 398C. Targetoid lesions and erosions developed on the trunk and extremities.
Erosions extended to the oral and genital mucosa, and covered more than 60% of the body
surface by day 25 (Fig 1, A). Blood work on day 18 showed profound leukocytopenia (\1.0 3 …