[HTML][HTML] Group-wide, prospective study of ototoxicity assessment in children receiving cisplatin chemotherapy (ACCL05C1): a report from the Children's Oncology …

KR Knight, L Chen, D Freyer, R Aplenc… - Journal of clinical …, 2017 - ncbi.nlm.nih.gov
KR Knight, L Chen, D Freyer, R Aplenc, M Bancroft, B Bliss, H Dang, B Gillmeister…
Journal of clinical oncology, 2017ncbi.nlm.nih.gov
Purpose Optimal assessment methods and criteria for reporting hearing outcomes in
children who receive treatment with cisplatin are uncertain. The objectives of our study were
to compare different ototoxicity classification systems, to evaluate the feasibility of including
otoacoustic emissions and extended high frequency audiometry, and to evaluate a central
review mechanism for audiologic results for cisplatin-treated children in the cooperative
group setting.
Abstract
Purpose
Optimal assessment methods and criteria for reporting hearing outcomes in children who receive treatment with cisplatin are uncertain. The objectives of our study were to compare different ototoxicity classification systems, to evaluate the feasibility of including otoacoustic emissions and extended high frequency audiometry, and to evaluate a central review mechanism for audiologic results for cisplatin-treated children in the cooperative group setting.
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