Extended post ex-vivo lung perfusion cold preservation predicts primary graft dysfunction and mortality: Results from a multicentric study
MM Leiva-Juárez, A Urso, EA Tomás… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Ex vivo lung perfusion (EVLP) allows for a reassessment of lung grafts
initially deemed unsuitable for transplantation, increasing the available donor pool;
however, this requires a pre-and post-EVLP period of cold ischemic time (CIT). Paucity of
data exists on how the sequence of cold normothermic–cold preservations affect outcomes.
METHODS A total of 110 patients were retrospectively analyzed. Duration of 3 preservation
phases was measured: cold pre-EVLP, EVLP, and cold post-EVLP. The donor and recipient …
initially deemed unsuitable for transplantation, increasing the available donor pool;
however, this requires a pre-and post-EVLP period of cold ischemic time (CIT). Paucity of
data exists on how the sequence of cold normothermic–cold preservations affect outcomes.
METHODS A total of 110 patients were retrospectively analyzed. Duration of 3 preservation
phases was measured: cold pre-EVLP, EVLP, and cold post-EVLP. The donor and recipient …