Endothelin—biology and disease

A Khimji, DC Rockey - Cellular signalling, 2010 - Elsevier
A Khimji, DC Rockey
Cellular signalling, 2010Elsevier
Endothelins are important mediators of physiological and pathophysiologic processes
including cardiovascular disorders, pulmonary disease, renal diseases and many others.
Additionally, endothelins are involved in many other important processes such as
development, cancer biology, wound healing, and even neurotransmission. Here, we review
the cell and molecular biology as well as the prominent pathophysiological aspects of the
endothelin system.
Endothelins are important mediators of physiological and pathophysiologic processes including cardiovascular disorders, pulmonary disease, renal diseases and many others. Additionally, endothelins are involved in many other important processes such as development, cancer biology, wound healing, and even neurotransmission. Here, we review the cell and molecular biology as well as the prominent pathophysiological aspects of the endothelin system.
Elsevier