Morphologic analysis of urinary podocytes in focal segmental glomerulosclerosis

Y Shirai, K Miura, T Yokoyama, S Horita… - Kidney360, 2021 - journals.lww.com
Background The development of glomerulosclerosis in FSGS is associated with a reduction
in podocyte number in the glomerular capillary tufts. Although it has been reported that the
number of urinary podocytes in FSGS exceeds that of minimal-change nephrotic syndrome,
the nature of events that promote podocyte detachment in FSGS remains elusive. Methods
In this study, we provide detailed, morphologic analysis of the urinary podocytes found in
FSGS by examining the size of the urinary podocytes from patients with FSGS, minimal …